development of this BioWeb site was supported by grants from AcITAC and The Foundation of UMDNJ.
The site is under continuous expansion and revision. For comments and
to use this material please contact Dr.
PowerPoint slides are
available only when the course is scheduled
(January to June) every year. All slides may
not be available at all times. Please e-mail
Dr. Kumar if you have
of biochemical terms
Asked Questions (FAQs)
Dr. Suriender Kumar (Course Director)
I received my B.Sc
(Honors) and M.Sc in chemistry
from Delhi University in 1960 and Ph.D. from
Boston University in 1967 under the direction of Dr. George Hein. I was
a post doctoral
fellow with Dr. George Hess (a member of the national academy of
sciences) at Cornell
and a research associate with Dr. John Porter at University of
Wisconsin at Madison.
In 1971, I joined the then CMDNJ at Newark as an assistant professor
and was promoted
to professor in 1981. Although I was trained as an enzymologist, I have
various fields of research including enzymology, cell transformation
and mechanism of bone
formation and bone resorption. Over the years, I have had numerous
research grants, have
had around 12 postdoctoral fellows trained in my laboratory, and have
published and reviewed
many papers in prestigious journals, including one major theoretical
paper. More recently
I have concentrated my efforts in teaching and service. At New Jersey
I have been a course director for Medical Biochemistry and I have been
for Dental Biochemistry for the past 12 years. I have interviewed
candidates for admission
to NJMS Medical School admissions committee and have been on the
at NJ Dental School for the past ~10 years. I have served on numerous
Upadhyay, Nootan Pandey, Suriender Kumar and Virendra N. Pandey. Role
of Tryptophan 24 and Phenylalanine 61 of HIV-1 RT in template
positioning, fidelity and conferring drug sensitivity to the enzyme.
(2010). Global J. Biochem. 1, 1-17
|B. Sharma, N.
Kaushik, K. Singh, S. Kumar, and V.
N. Pandey.(2002) Substitution of Conserved Hydrophobic Residues in
Motifs B and C of HIV-1 RT Alters the Geometry of Its Catalytic Pocket.
Biochemistry 41, 15685-15697.
|P.K. Pandey, N.
Kaushik, D. Harris, B. Sharma, K.
Singh, S. Kumar and V.N. Pandey. (2002). Insertion of a small peptide
of 6 amino acids in the b7-b8 Loop of the p51 Subunit of HIV-1 Reverse
Transcriptase Prevents Dimerization and Disrupts Enzymatic Activities.
BMC-Biochemistry 3(1): 18
|Chang, K.M., Rani, S., Chang, K.C. and Kumar, S.
(1996) Plasminogen activator activity is decreased in rat gingiva
during diabetes. J. Periodontology, 67, 743-747
F.S., Jandinski, J.J., Feder,
L., and Kumar, S. (1995) Heparin fails to potentiate the effects of
IL-1¿-mediated bone resorption of fetal rat long bones in vitro.
BIochemie, 77, 915-918. Panagakos, F.S., Fernandez, C., and Kumar, S.
(1996) Ultrastructural analysis of mineralized matrix from human
osteoblastic cells: Effects of tumor necrosis factor-¿. Mol.
Cell. Biochem. 158, 81-89.
|Shah, V. and Kumar, S. (1994) Metastasis of human
colon tumor cells in vitro: Correlation with the overexpression of
plasminogen activators and 72-kDa gelatinase. In Vivo, 8, 321- 326.
|Panagakos, F.S., Hinojosa, L.P. and Kumar, S.
(1994) Formation and mineralization of extracellular matrix secreted by
an immortal human osteoblastic cell line: Modulation by tumor necrosis
factor-alpha. Inflammation, 18, 267-283.
|Rani, A.S., Qu, D.Q., Sidhu, M.K., Panagakos, F.,
Shah, V., Klein, K., Brown, N., Pathak, S. and Kumar, S. (1993)
Transformation of immortal non-tumorigenic osteoblast like human
osteosarcoma cells to the tumorigenic phenotype by nickel sulfate.
Carcinogensis, 14, 947- 953.
|Rani, A., Shobha
and Kumar, S. (1992)
Transformation of nontumorigenic osteoblast-like human osteosarcoma
cells by hexavalent chromates: Alteration of morphology, induction of
anchorage-independence and proteolytic function. Carcinogenesis, 13,
|Kumar, S. (1982) A model for the mechanism of
action of animal fatty acid synthases. J. Theor. Biol., 95, 263-283.