Basic Research  
  The Center for Refractive Surgery and Cornea Research is dedicated to developing and improving techniques for cornea surgery. The Institute also houses The Division of Applied Optics. Here, physicians and scientists with diverse interests are brought together to study the application of optical principles to clinical problems and to develop low vision aids for patients with age-related macular degeneration. The Cornea and Laser Vision Institute is situated at Glenpointe Centre East and is run jointly with Hackensack University Medical Center. Dr. Peter S. Hersh directs these centers.  
  Analysis of Corneal Topography Following Excimer Laser Photorefractive Refractive Keratectomy and Conductive Keratoplasty  
  Peter S. Hersh, MD  
  Dr. Hersh is analyzing corneal topography following excimer laser photorefractive keratectomy (LASIK and PRK). Dr. Hersh is the principal investigator on a number of clinical trials. His investigations include the relationship and influence of corneal topography patterns on clinical outcome, analysis of new quantitative descriptors of corneal topography, and optimization of the postoperative corneal contour.  
  Corneal Topography After Laser Refractive Surgery  
  Peter S. Hersh, MD  
  Dr. Hersh is studying the optical topography effects of LASIK for farsightedness and astigmatism. In addition, the effect(s) of lamellar corneal flaps on optical topography are being investigated. Comparative clinical studies looking at safety and efficacy of LASIK vs PRK are ongoing.  
  Corneal Biomechanical Effects of LASIK Flap on Optical Outcomes  
  Peter S. Hersh, MD  
  Dr. Hersh is studying the effects of the lamellar corneal flap in laser in situ keratomileusis. Early results, recently published by his group, show meridional optical changes based on flap position. Such research should aid in resolving the influences on postoperative outcome after laser refractive surgery.  
  Cornea Imaging With Optical Coherent Tomography  
  David Chu, MD  
  Dr. Chu is examining the usefulness of using optical coherent tomography (OCT) in cross-sectional imaging of the cornea and pathologic cornea, eg, corneal scars and pterygia.  
  Corneal Immunology After Mechanical and Chemical Injuries OLD  
  David Chu, MD  
  The goal of Dr. Chu’s research is to determine the expression of various inflammatory fibrotic factors associated with superficial injury to the cornea, particularly after refractive surgical procedures. Dr. Chu is trying to establish a model for diffuse lamellar keratitis, an unusual but devastating complication of LASIK surgery.  

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