Quiz Case #2
Clinical Presentation:
A 60-year-old male presented with a pathologic fracture of the right proximal humerus. His prior medical history was non-contributory.
Look at the
AGE
and
SKELETAL LOCATION
.
Radiological Findings
:
Plain radiograph demonstrates a large,
ill-defined
, vaguely lobulated tumor
centered in the metaphysis
. Note
stippled and ringed calcifications
, peripheral radiolucencies and cortical disruption.
MRI
Pathological Findings:
:
Microscopic findings, low magnification
High magnification
Questions
Q.1 What is your diagnosis?
1
Enchondroma
2
Chondrosarcoma, Grade I
3
Chondrosarcoma, Grade II
4
Chondromyxoid fibroma
Q2. What histologic parameters are assessed in grading of these tumors?
1
Cellularity
2
Degree of nuclear atypia
3
Mitotic activity
4
All of the above
This is a self-assessment test. The results are neither collected nor stored.
