Quiz Case #4
Clinical Presentation:
A 16-year-old male was seen in consultation for a painful lesion of the proximal humerus.
Radiological Findings
:
Plain film showing a
destructive lesion
in the proximal humeral
metaphysis
.
Pathological Findings:
:
Biopsy specimen, low magnification
High magnification
Questions
Q1. What is your diagnosis?
1
Osteosarcoma, high grade
2
Osteosarcoma, well-differentiated (low-grade)
3
Aggressive osteoblastoma
4
MFH
Q2. What is the distinguishing and diagnostic feature of this tumor?
1
Highly pleomorphic mesenchymal cells
2
Tumor osteoid
3
Characteristic immunophenotype
4
Characteristic chromosomal abnormality
Q3. Prognosis depends on
1
Tumor response to pre-operative chemotherapy
2
Surgical stage
3
Skeletal site of involvement
4
All of the above
This is a self-assessment test. The results are neither collected nor stored.