UNIVERSITY OPHTHALMOLOGY CONSULTANTS

 

CASE OF THE MONTH

CASE #19

 

 
HOW SHOULD THE PATIENT BE TREATED AT THIS POINT?
  • Intravenous acyclovir (400 mg, bid) was added to the medical regimen, which also included ganciclovir.
  • Cyclosporine was discontinued 5 days after onset of visual loss.
  • Cyclophosphamide, 50 mg, po, qd, and tacrolimus, 1 mg, po, qd, were prescribed.
  • The prednisone dose was increased to 30 mg, po, bid.

 11 DAYS AFTER INITIAL EVALUATION: Ganciclovir was withdrawn because we believed that  the patient did not have a CMV-induced infection. Acyclovir was also temporarily withdrawn in  preparation for a diagnostic vitreous tap on the 11th day of follow-up. After the diagnostic  procedure, the renal transplant team resumed administration of acyclovir as routine prophylactic  therapy following renal transplantation.

 CLINICAL COURSE: Over the next 3 weeks, the patient’s visual acuity progressively deteriorated  to hand motion at 1foot (OD) and counting fingers at 1 foot (OS).

 

Click to view the fundus image OD at this clinical stage
       
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