2017

• Neuberger EJ, Gupta A, Subramanian  D,  Korgaonkar AA,  Santhakumar, V (2017) Converging early responses to brain injury pave the road to epileptogenesis. J.Neurosci.Res, doi: 10.1002/jnr.24202.
• Neuberger EJ, Swietek B, Corrubia L, Prasanna A, Santhakumar, V.(2017) Enhanced Dentate Neurogensis after Brain Injury Undermines Long -Term Neurogenic Potential and Promotes Seizure Susceptibility. Stem Cell Reports 2017 Sep 12;9(3):972-984. doi: 10.1016/j.stemcr.2017.07.015.
• Subramanian, D, Santhakumar, V (2017). Lighting the Fuse: Deconstucting Complex Network Interactions Using On-Demand Seizures. Epilepsy Currents Invited Commentary, May-Jun;17(3):174-176.

2016

• Swietek, B., Gupta, A., Proddutur, A., Santhakumar, V.(2016) Immunostaining of Biocytin-filled and Processed Sections for Neurochemical Markers. J. Vis. Exp. (118), e54880, doi:10.3791/54880.
• Gupta, A, Santhakumar, V (2016). Illuminating the Role for Chloride Dysregulation in Network Activity. Epilepsy Currents, Jul-Aug;16(4):258-260.
• Abdul-Muneer PM, Long M, Conte AA, Santhakumar V, Pfister BJ, (2016). High Ca2+ influx during traumatic brain injury leads to Caspase-1-Dependent neuroinflammation and cell death. Molecular Neurobiology. DOI:10.1007/s12035-016-9949-4.
• Murugan M, Santhakumar V, Kannurpatti S (2016). Activation-induced spatiotemporal cerebral blood flow changes and behavioral deficit after mTBI in immature rats can be favorably altered by facilitating mitochondrial calcium uptake. Frontiers in Systems Neuroscience. DOI: 10.3389/fnsys.2016.00019.
• Proddutur A, Santhakumar V (2016). Fingerprints of interictal spikes: Can imprints deliver a verdict on their role in epilepsy? Epilepsy Currents. Jan-Feb;16(1):41-2. DOI: 10.5698/1535-7597-16.1.41.
• Yu J, Swietek B, Proddutur A, Santhakumar V (2016). Dentate cannabinoid-sensitive interneurons undergo unique and selective strengthening of mutual synaptic inhibition in experimental epilepsy. Neurobiology of Disease. Jan, 21; 89:23-35. DOI:10.2016/j.nbd.2016.01.013.

• Proddutur A, Santhakumar V (2015). Marching towards a Seizure: Spatio-temporal Evolution of Preictal activity., Epilepsy Currents.Sep-Oct; 15(5): 267–268.
• Yu J, Proddutur A, Swietek B, Elgammal F, Santhakumar V (2015). Functional reduction in Cannabinoid-Sensitive Heterotypic Inhibition of Dentate Basket Cells in Epilepsy: Impact on Network Rhythms. Cerebral Cortex. DOI: 10.1093/cercor/bhv199.
• Wahab RA, Neuberger EJ, Lyeth BG, Santhakumar V, Pfister BJ (2015)., Percussion Injury Device for the Precise Control of Injury Parameters. Journal of Neuroscience Methods. Jun 15;248:16-26. DOI: 10.1016/j.jneumeth.2015.03.010.
• Yu J, Swietek B, Proddutur A, Santhakumar V, (2015)., Dentate total molecular layer interneurons mediate cannabinoid-sensitive inhibition. Hippocampus. Aug;25(8):884-9. DOI: 10.1002/hipo.22419.
• Li Y*, Korgaonkar A*, Swietek B , Wang J, Elgammal FS, Elkabes, S,Santhakumar V (2015). Toll-like receptor 4 augments mossy cell AMPA currents and contributes to NMDA receptor-independent increase in dentate excitability after brain injury. Neurobiology of Disease. DOI: 10.1016/j.nbd.2014.11.021* Equal Contribution.

• Pang KCH, Sinha S, Avcu P, Roland JJ, Nadpara N, Pfister BJ, Long M,   Santhakumar V, Servatius RJ. (2014)., Long-lasting suppression of acoustic startle response following mild traumatic brain injury. Journal of Neurotrauma. DOI:10.1089/neu.2014.3451.
• Ordek G, Proddutur A, Santhakumar V, Pfister BJ, Sahin M (2014)., Electrophysiological Monitoring of Injury Progression in the Rat Cerebellar Cortex. Frontiers in Systems Neuroscience Oct 9;8:197. DOI: 10.3389/fnsys.2014.00197. eCollection 2014.
• Neuberger EJ*, Abdul Wahab R, Jaykumar A, Pfister BJ, SSanthakumar V (2014)., Distinct effect on impact rise times on immediate and early neuropathology after brain injury in juvenile rats. Journal of Neuroscience Research. 05 May 2014.

• Proddutur A*, Yu J, Elgammal FS, Santhakumar V (2013)., Seizure-induced alterations in fast-spiking basket cell GABA currents modulate frequency and coherence of gamma oscillation in network simulations. Chaos. 20 November. 23, 046109.
• Santhakumar V, Pratap M*, Karakossian MH*, Otis TS (2013)., A reinforcing circuit action of extrasynaptic GABA(A) receptor modulators on cerebellar granule cell inhibition. PLOS ONE 2013 Aug 19;8(8):e72976.
• Yu J*, Proddutur A*, Elgammal FS, Ito T,   Santhakumar V (2013)., Status epilepticus enhances tonic GABA currents and depolarizes GABA reversal potential in dentate fast-spiking basket cells. The Journal of Neurophysiology 109: 1746-1763. Also featured in Global Medical Discovery.

• Gupta A, Elgammal FS*, Proddutur A*, Shah S,   Santhakumar V (2012)., Decrease in Tonic Inhibition Contributes to Increase in Dentate Semilunar Granule Cell Excitability after Brain Injury. The Journal of Neuroscience 32(7): 2523-2537.Also featured in Psychology Progress

• Santhakumar V, Jones RT., Mody I (2010)., Developmental Regulation and Neuroprotective Effects of Striatal Tonic GABAa Currents. Neuroscience 167(3):644-55.

• Santhakumar V, Wallner M, Otis TS, (2007)., Ethanol acts Directly on Extrasynaptic Subtypes of GABAa Receptors to Increase Tonic Inhibition. Alcohol 41(3):211-221.
• Dyhrfjeld-Johnsen J*, Santhakumar V*, Morgan R, Huerta R, Tsimring L, Soltesz I (2007).,  Topological Determinants of Epileptogenesis in Large-Scale Structural and Functional Models of the Dentate Gyrus Derived from Experimental Data. Journal of Neurophysiology 97(2):1566-1587.

• Santhakumar V, Hanchar HJ, Wallner M, Olsen RW & Otis TS (2006)., Contributions of the GABAA Receptor Subunit a6 to Phasic and Tonic Inhibition Revealed by a Naturally Occurring Polymorphism in the a6 Gene. Journal of Neuroscience 26(12):3357 –3364.

• Santhakumar V, Aradi I, Soltesz I (2005)., Role of Mossy Fiber Sprouting and Mossy Cell Loss in Hyperexcitability: A Network Model of the Dentate Gyrus Incorporating Cell Types and Axonal Topography. Journal of Neurophysiology 93(1):437-53.

• Aradi I*, Santhakumar V*, Soltesz I (2004)., Simple Rules Govern the Impact of Heterogeneous Perisomatic IPSC Populations on Pyramidal Cell Firing Rates. Journal of Neurophysiology 91: 2849–2858.
• Ratzliff AH, Howard A, Santhakumar V, Osapay I, Soltesz I (2004)., Rapid Deletion of Mossy Cells Does Not Result in a Hyperexcitable Dentate Gyrus: Implications for Epileptogenesis. Journal of Neuroscience 24(9):2259 –2269.

• Santhakumar V, Voipio J, Kaila K, Soltesz I (2003).,  Post-traumatic hyperexcitability is not caused by impaired buffering of extracellular potassium. Journal of Neuroscience 23(13):5865-76.

• Aradi I, Santhakumar V, Chen K, Soltesz I (2002)., Postsynaptic effects of GABAergic synaptic diversity: regulation of neuronal excitability by changes in IPSC variance. Neuropharmacology 43: 511-522.

• Santhakumar V, Ratzliff AD, Jeng J, Toth K, Soltesz I (2001).,   Long-term hyperexcitability in the hippocampus after experimental head trauma. Annals of Neurology 50: 708-717.

• Santhakumar V, Bender R, Frotscher M, Ross ST, Hollrigel GS, Toth Z, Soltesz I (2000)., Granule cell hyperexcitability in the early post-traumatic rat dentate gyrus: the 'irritable mossy cell' hypothesis. Journal of Physiology (London) 524 Pt 1: 117-134.

• Veerasammy S, Kumari E, Goodus MT,  Neuberger EJ, , Santhakumar V  and Levison SW  (2017) . Consequences of Inflammation Within Neural Stem Cell Niches On Development And Regeneration In The Immature Brain. 2nd edition  of the Frontiers in Stem Cell and Regenerative Medicine research e-Book, edited by Drs. Atta-Ur-Rahman and Anjum. Vol.7, 43-91.
• Santhakumar V (2008), Modeling mossy cell loss and mossy fiber sprouting in epilepsy In: Computational Neuroscience in Epilepsy edited by Soltesz I and Staley K.J. Academic Press. 89-111.
• Morgan R, Santhakumar V, Soltesz I (2007), Modeling the Dentate Gyrus In: The Dentate Gyrus edited by Scharfman H. Elsevier press. Progress in Brain Research 163C:639-658.

• Santhakumar V and Soltesz I (2004) Heterogeneity on the Move: Plasticity of Interneuronal Species Diversity and Parameter Variance in Neurological Diseases. Trends in Neuroscience 27(8):504-10.
• Chen K, Aradi I, Santhakumar V, Soltesz I (2002) H-channels in epilepsy: new targets for seizure control? Trends in Pharmacological Sciences 23: 552-557.
• Ratzliff AH, Santhakumar V, Howard A, Soltesz I (2002) Mossy cells in epilepsy: rigor mortis or vigor mortis? Trends in Neuroscience 25: 140-144.